Boswellia serrata

Boswellia serrata

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Boswellia serrata
in Kinnerasani Wildlife Sanctuary, Andhra Pradesh, India.
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Rosids
Order: Sapindales
Family: Burseraceae
Genus: Boswellia
Species: B. serrata
Binomial name
Boswellia serrata
Triana & Planch.

Boswellia serrata is Indian frankincense or Salai. It is found in Rajasthan, Madhya Pradesh & Andhara Pradesh in India.



[edit] Medical usage

In Ayurvedic medicine Indian frankincense (Boswellia serrata) has been used for hundreds of years for treating arthritis.[1]

Extracts of Boswellia serrata have been clinically studied for osteoarthritis and joint function, particularly for osteoarthritis of the knee. Positive effects of Boswellia in some chronic inflammatory diseases including rheumatoid arthritis, bronchial asthma, osteoarthritis, ulcerative colitis and Crohn's disease have been reported.[2] A Boswellia extract marketed under the name Wokvel has undergone human efficacy, comparative, pharmacokinetic studies.[3][4][5]

Boswellia serrata is used in the manufacture of the supposed anti-wrinkle agent "Boswelox",[6] which has been criticised as being ineffective.[7]

[edit] Potential for anti-cancer activity

Boswellic acid, an extract from Boswellia serrata, has been studied for anti-neoplastic activity, especially in experimental primary and secondary brain tumors, indicating potential efficacy from in vitro[8][9] and limited clinical research.[10] Boswellic acid is also undergoing an early-stage clinical trial at the Cleveland Clinic.[11]

[edit] External links

[edit] References

  1. ^ "JOINT RELIEF". Retrieved 2009-01-12.
  2. ^ Ammon HP."Modulation of the immune system by Boswellia serrata extracts and boswellic acids. [Review]" Phytomedicine. 17(11):862-7, 2010 Sep.
  3. ^ Open, randomized, controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of knee. Indian Journal of Pharmacology. 2007; 39(1) 27-29
  4. ^ Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.
  5. ^ Pharmacokinetic study of 11-Keto beta-Boswellic acid. Phytomedicine. 2004 Feb;11(2-3):255-60.
  6. ^ Wrinkle breakthrough claim from L'Oreal
  7. ^ L'Oreal slammed over cream claims
  8. ^ Acetyl-11-Keto-β-Boswellic Acid Inhibits Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2–Mediated Angiogenesis
  9. ^ LY294002 Enhances Boswellic Acid-induced Apoptosis in Colon Cancer Cells
  10. ^ A lipoxygenase inhibitor in breast cancer brain metastases
  11. ^ Phase II Randomized Evaluation of 5-Lipoxygenase Inhibition by Herbal Medicine Approach Compared to Control as an Adjuvant Therapy in Newly Diagnosed and Recurrent High-Grade Gliomas

[edit] Gallery